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Dr Wise: Cannabis Scientist Answers Questions in Wired Twitter Q&A

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Step into the enlightening realm of cannabis science with Dr. Amber Wise, a renowned expert dedicated to untangling the complexities of this intriguing plant. In this informative video, Dr. Wise addresses a series of burning questions that have been buzzing on the web about cannabis.

Ever found yourself pondering the intricate differences between the Indica and Sativa strains of cannabis? Or perhaps you’re questioning whether CBD truly offers any beneficial effects? Maybe you’re intrigued by the distinctive fragrance exuded by cannabis, or you’re wondering about the health ramifications of consuming weed on a daily basis. These are the kinds of topical queries that Dr. Wise expertly navigates in this video.

Her approach is an engaging blend of robust scientific data, backed by her comprehensive knowledge and years of experience in the field of cannabis research. She meticulously explains the genetic factors that contribute to the differences between Indica and Sativa strains, the scientific evidence behind the effects of CBD, and the chemical intricacies that give rise to the unique scent of cannabis. Furthermore, she tackles the controversial topic of daily cannabis consumption, providing balanced perspectives informed by the latest research.

This video, featuring Dr. Wise’s expertise, is more than just a Q&A – it’s an educational journey that sheds light on the multifaceted world of cannabis. You’ll gain insights into the physiological, genetic, and societal aspects of cannabis use, promoting a greater understanding and fostering informed discussions.

So why wait? Immerse yourself in this enlightening video and let Dr. Wise guide you through the fascinating maze of cannabis science. This isn’t just a summary – it’s an invitation to broaden your knowledge and engage with the captivating world of cannabis in a whole new way. Prepare to have your burning questions answered, and much more!


The video explores various facts and myths about cannabis, including its medical benefits, molecular profiles, effects on sleep and dreams, safety, and legal status.

  • 🌿 Cannabis has medical benefits, stimulates hunger, and has become stronger through selective breeding, but labels claiming over 30% THC in flower are inaccurate due to a physical limit.
  • Cannabis can be used for medical purposes; cannabinoids stimulate hunger, and our body produces its own cannabinoids, and cannabis has become stronger due to selective breeding.
  • Labels claiming over 30% THC in cannabis flower are not accurate as there is a physical limit to the amount the plant can produce.
  • 🧠 Psychoactive substances affect brain chemistry and perception of reality, while CBD and THC have different effects due to their molecular structures and edibles hit differently because they go through the liver.
  • Psychoactive substances react with brain chemistry, psychotropic substances affect perception of reality, and psychedelic substances include hallucinations and drastic changes in perception of reality, with THC being considered psychotropic but cannabinoids not generally considered psychedelic.
  • CBD and THC have similar molecular structures, but their different shapes lead to different effects on the body, and edibles hit differently because they go through the liver and create different molecules.
  • 🌿 Outdoor and indoor weed have different molecular profiles, with outdoor having a wider variety of cannabinoids and indoor often having higher yield and more consistent profiles, while terpenes and trichomes play a role in the distinctive smell and synthesis of cannabinoids and recent studies suggest the difference between indica and sativa might be a myth.
  • Indoor and outdoor weeds have different molecular profiles, with outdoor having a wider variety of cannabinoids and indoor often having higher yields and more consistent profiles.
  • Terpenes are responsible for the distinctive smell of cannabis, trichomes are where cannabinoids and terpenes are synthesised, and recent studies suggest that the difference between Indica and Sativa might just be all in your head.
  • 💤 THC and CBD can aid in sleep but reduce dream recall, while secondhand smoke can result in a positive THC test but can be eliminated with ventilation.
  • THC and CBD can help with falling asleep but reduce REM cycles, leading to less dream recall, and the plant benefits from making these molecules as secondary metabolites, while the release of the anandamide molecule in the brain causes the “high” from weed.
  • Inhaling secondhand smoke in a stuffy room can result in a positive THC test and feeling a little high, but ventilating the room can eliminate these effects.
  • 🌿 Weed originated in East Asia and China 12,000 years ago and makes you laugh by increasing blood flow to the prefrontal cortex and endocannabinoid molecules.
  • Delta-8, 9, and 10 are distinguished by the position of a double bond, with Delta-9 being naturally produced by the plant and Delta-8 and Delta-10 being converted from CBD or Delta-9.
  • Weed makes you laugh because it increases blood flow to the prefrontal cortex and endocannabinoid molecules, and cannabis originated from East Asia and China about 12,000 BC with evidence of psychotropic and spiritual use 7,500 years ago.
  • 🌿 Cannabis is generally safer than other recreational drugs but can cause dry mouth and addiction.
  • Cannabinoids in weed interact with neurotransmitters in our brains, causing our saliva glands to stop working, and while addiction to cannabis is possible, it is generally much safer than other types of recreational drugs.
  • 🌿 Cannabis can treat cancer, glaucoma, and multiple sclerosis, but it remains a schedule 1 drug due to bureaucratic obstacles and legal issues.
  • Cannabis can help with the treatment of cancer, chemotherapy side effects, glaucoma, and multiple sclerosis, but it is still classified as a schedule 1 drug.
  • The DEA and FDA are pointing fingers at each other for obstructing the rescheduling of marijuana, but it would be better to deschedule it altogether due to limitations and legal and social justice issues.
  • 🌿 Weed turns purple due to UV protectors called anthocyanins, and resin, live resin, and rosin are different types of sticky oils or extracts.
  • Weed turns purple due to molecules called anthocyanins, which are UV protectors and can absorb extra UV energy. The difference between resin, live resin, and rosin is that resin is a general term for all kinds of sticky oils or extracts; live resin is extracted from fresh frozen plant material, and rosin is pressed oil from the plant itself.


  • 🌿 Humans have been selectively breeding cannabis for a long time to make it stronger, with more cannabinoids in the flower than 30-40 years ago.
  • 🍪 Edibles hit differently because they go through your stomach, intestines, and liver, causing a different molecule to form, called “11-Hydroxy-THC”.
  • 🌿 Cannabis trichomes are where all of the cannabinoids and terpenes are synthesized in the plant, making them incredibly important for the plant’s effects and potency.
  • 💤 THC and CBD in combination can help with falling asleep, but THC reduces REM cycles, affecting dream recall.
  • 😂 The mechanism behind why weed makes you laugh is that it increases the endocannabinoid “bliss molecules” in our bodies, affecting our moods.
  • 🌿 Cannabis can be a potential solution for getting off other types of drugs like opiates.
  • 💊 Cannabis has been shown to help with the treatment of cancer and a lot of the side effects that come from chemotherapy and radiation, making you feel hungry which is important to keep your nutrition up, and helping you sleep and relax, which is good for healing, and the nausea that you can sometimes get with chemotherapy.
  • 🍯 “Live resin” is extracted from fresh frozen plant material, while “rosin” is pressed oil from dried flower buds without solvents.